Recombinant Human Cadherin-17 His (C-Term) Protein

SDS-Page: Recombinant Human Cadherin-17 His (C-Term) Protein [NBP3-18199] - Recombinant Human Cadherin-17 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 105-115 kDa.

• Reactivity: Hu
• Applications: PAGE
• Concentration: LYOPH

Recombinant Human Cadherin-17 His (C-Term) Protein Summary

• Description: A recombinant protein with a C-terminal 6xHis tag corresponding to the amino acids Gln23-Met787 of Human Cadherin-17.

  Source: HEK293

  (Accession #: NP_001138135.1)
  
  Store at -20C to -80C long term. After reconstitution, the product is stable at -20C for 3 months, and 2-8C for up to 1 week.

• Source: HEK293
• Protein/Peptide Type: Recombinant Protein
• Gene: CDH17
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: < 0.1 EU/ug of the protein by LAL method

Applications/Dilutions

• Dilutions:
  • SDS-Page

Packaging, Storage & Formulations

• Storage: Store at -20C.
• Buffer: Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4
• Concentration: LYOPH
• Purity: >90%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water

Alternate Names for Recombinant Human Cadherin-17 His (C-Term) Protein

• cadherin 17, LI cadherin (liver-intestine)
• cadherin
• cadherin-16
• Cadherin17
• Cadherin-17
• CDH16
• CDH17
• FLJ26931
• HPT-1 cadherin
• HPT1
• HPT-1
• human intestinal peptide-associated transporter HPT-1
• human peptide transporter 1
• Intestinal peptide-associated transporter HPT-1
• LI cadherin
• LI-cadherin
• Liver-intestine cadherin
• MGC138218
• MGC142024

Background

LI Cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CDH17