Cadherin-17 Antibody (MM0121-6G13) - Azide and BSA Free

• Reactivity: Hu
• Applications: WB, IHC
• Clone: MM0121-6G13
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

Cadherin-17 Antibody (MM0121-6G13) - Azide and BSA Free Summary

• Immunogen: Human recombinant Cadherin-17
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CDH17
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:20-1:100
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for Cadherin-17 Antibody (MM0121-6G13) - Azide and BSA Free

• cadherin 17, LI cadherin (liver-intestine)
• cadherin
• cadherin-16
• Cadherin17
• Cadherin-17
• CDH16
• CDH17
• FLJ26931
• HPT-1 cadherin
• HPT1
• HPT-1
• human intestinal peptide-associated transporter HPT-1
• human peptide transporter 1
• Intestinal peptide-associated transporter HPT-1
• LI cadherin
• LI-cadherin
• Liver-intestine cadherin
• MGC138218
• MGC142024

Background

LI Cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cadherin-17 Antibody (NBP2-12065)(1)

Publication using NBP2-12065

• Varani J, McClintock SD, Nadeem DM et al. A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids Frontiers in cell and developmental biology 2023-07-05 [PMID: 37476158] (IHC, Human)
  
  Details:
  1:200 dilution

Bioinformatics

• Gene Symbol: CDH17
• Uniprot:
  • CAA58231()