CACNA1E Antibody - BSA Free

Western Blot: CACNA1E Antibody [NBP2-92004] - Analysis of extracts of various cell lines, using CACNA1E at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CACNA1E Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CACNA1E Antibody - BSA Free (NBP2-92004) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2014-2313 of human CACNA1E (NP_001192222.1). PSSMRRSFSTIRDKRSNSSWLEEFSMERSSENTYKSRRRSYHSSLRLSAHRLNSDSGHKSDTHRSGGRERGRSKERKHLLSPDVSRCNSEERGTQADWESPERRQSRSPSEGRSQTPNRQGTGSLSESSIPSVSDTSTPRRSRRQLPPVPPKPRPLLSYSSLIRHAGSISPPADGSEEGSPLTSQALESNNACLTESSNSPHPQQSQHASPQRYISEPYLALHEDSHASDCGEEETLTFEAAVATSLGRSNTIGSAPPLRHSWQMPNGHYRRRRRGGPGPGMMCGAVNNLLSDTEEDDKC
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CACNA1E
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CACNA1E Antibody - BSA Free

• BII
• Brain calcium channel II
• CACH6
• CACH6calcium channel, R type, alpha-1 polypeptide
• CACNA1E
• CACNL1A6
• CACNL1A6calcium channel, voltage-dependent, alpha 1E subunit
• calcium channel, voltage-dependent, R type, alpha 1E subunit
• Cav2.3
• L type, alpha-1 polypeptide
• L type, alpha-1 polypeptide, isoform 6
• voltage-dependent calcium channel alpha 1E subunit
• voltage-dependent R-type calcium channel subunit alpha-1E
• voltage-gated calcium channel alpha 1E subunit
• Voltage-gated calcium channel subunit alpha Cav2.3

Background

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels contaning alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Expressed in neuronal tissues and in kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CACNA1E