C1QB Antibody (C1QB/2965) [Janelia Fluor® 585]

Product Discontinued

C1QB Antibody (C1QB/2965) [Janelia Fluor® 585] Summary

• Immunogen: Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary) (Uniprot: P02746)
• Localization: Cytoplasmic, Cell Surface
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: C1QB
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for C1QB Antibody (C1QB/2965) [Janelia Fluor® 585]

• B chain
• complement C1q subcomponent subunit B
• complement component 1, q subcomponent, B chain
• complement subcomponent C1q chain B
• q subcomponent, beta polypeptide

Background

C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C1QB