BRCAA1 Antibody [DyLight 755]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 755

BRCAA1 Antibody [DyLight 755] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Reacts with residues 1046-1055 [SSKKQKRSHK] of the 136 kDa human, mouse and rat BRCAA1 protein.
• Specificity: BRCAA1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARID4B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-682. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Human, Mouse, Rat

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BRCAA1 Antibody [DyLight 755]

• 180 kDa Sin3-associated polypeptide
• ARID domain-containing protein 4B
• AT rich interactive domain 4B (RBP1- like)
• AT rich interactive domain 4B (RBP1-like)
• AT-rich interactive domain-containing protein 4B
• BRCAA1DKFZp313M2420
• breast cancer-associated antigen 1
• Breast cancer-associated antigen BRCAA1
• breast carcinoma-associated antigen
• Histone deacetylase complex subunit SAP180
• Rb-binding protein homolog
• RBBP1L1RBP1L1BCAA
• RBP1-like protein
• retinoblastoma binding protein 1-like 1
• Retinoblastoma-binding protein 1-like 1
• SAP180MGC163290
• SIN3A-associated protein 180
• Sin3-associated polypeptide p180

Background

ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARID4B