Western Blot: BORIS Antibody (20B11) [NBP2-52405] - Antibody from clone 20B11 specifically recognises the C terminal domain of BORIS, and the endogenous and exogenous BORIS protein. Cell lysates were resolved by ...read more
Immunohistochemistry: BORIS Antibody (20B11) [NBP2-52405] - Analysis using the supernatants from the clone 20B11 at following dilutions: (A) 20B11 undiluted supernatant and (B) 20B11 at 1:25. (B) Cells have been ...read more
Immunoprecipitation: BORIS Antibody (20B11) [NBP2-52405] - The 83-kDa protein can be immunoprecipitated with the mouse anti- BORIS C terminal specific antibody. Proteins were immunoprecipitated from the MCF7 cell ...read more
83 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publication using NBP2-52405 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Protein A purified
Alternate Names for BORIS Antibody (20B11) - BSA Free
Brother of the regulator of imprinted sites
Cancer/testis antigen 27
CCCTC-binding factor (zinc finger protein)-like
putative high mobility group protein 1-like 1
putative high mobility group protein B1-like 1
transcriptional repressor CTCFL
Zinc finger protein CTCF-T
BORIS (Brother of the Regulator of Imprinted Sites) also known as CCTC-binding factor-like protein, is normally only expressed in the testis and expressed in a mutually exclusive manner with CTCF during male germ cell development. However, previous studies have shown that BORIS is abnormally activated in a wide range of human cancers. Expression of BORIS in normally BORIS-negative cells promotes cell growth that may lead to transformation. BORIS maps to the cancer-associated amplification region thought to contain an oncogene or dominant-immortalizing gene. BORIS is a candidate protein for the epigenetic reprogramming factor acting in the male germ line. BORIS is found in both the nucleus and cytoplasm.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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