BMPR-IA/ALK-3 Antibody

Images

 
Western Blot: BMPR-IA/ALK-3 Antibody [NBP2-15601] - A. 40 ug 293T whole cell lysate/extract. B. 40 ug HepG2 whole cell lysate/extract. C. 15 ug whole cell lysate/extract of human BMPR1A-transfected 293T cells.
Western Blot: BMPR-IA/ALK-3 Antibody [NBP2-15601] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa 7. 5% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

BMPR-IA/ALK-3 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human BMPR1A. The exact sequence is proprietary.
Localization
Membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BMPR1A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Rhesus Monkey.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BMPR-IA/ALK-3 Antibody

  • ACVRLK310q23del
  • ALK-3
  • ALK3EC 2.7.11.30
  • BMP type-1A receptor
  • BMPR1A
  • BMPR-1A
  • BMPRIA
  • BMPR-IA
  • bone morphogenetic protein receptor type-1A
  • bone morphogenetic protein receptor, type IA
  • CD292 antigen
  • CD292
  • EC 2.7.11
  • Serine/threonine-protein kinase receptor R5
  • SKR5
  • type II-like kinase 3

Background

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol BMPR1A
Entrez
Uniprot