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HAF017). A specific band was detected for BMPR-IA/ALK-3 at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
VC006). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to epithelial cells and stroma. Staining was performed using our IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank">
653-E3) was serially diluted and captured by Mouse Anti-Human CCL26/Eotaxin‑3 Monoclonal Antibody (Catalog # MAB653) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human BMPR‑IA/ALK‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF346) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
314-BPE) was measured at a concentration range between 0.061 nM and 125 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=0.150 nM. (Biacore T200)." class="big_lightbox" target="_blank">
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
![Western Blot BMPR-IA/ALK-3 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/BMPR-IA_AF346_Western_Blot_9327.jpg)
![Surface Plasmon Resonance (SPR) BMPR-IA/ALK-3 [Unconjugated]](http://images.novusbio.com/images/2406-br_recombinant-human-bmpr-ia-alk-3-fc-chimera-protein-cf-surface-plasmon-resonance-spr-2492025143154.png)
![Immunohistochemistry BMPR-IA/ALK-3 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/af346_human-bmpr-ia-alk-3-affinity-purified-polyclonal-ab-immunohistochemistry-35202018211.jpg)
![Western Blot BMPR-IA/ALK-3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af346_human-bmpr-ia-alk-3-affinity-purified-polyclonal-ab-western-blot-12122025822317.jpg)
![Western Blot BMPR-IA/ALK-3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af346_human-bmpr-ia-alk-3-affinity-purified-polyclonal-ab-western-blot-121220258152618.jpg)
![Western Blot BMPR-IA/ALK-3 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af346_human-bmpr-ia-alk-3-affinity-purified-polyclonal-ab-western-blot-12122025822247.jpg)
![ELISA BMPR-IA/ALK-3 Antibody [Unconjugated]](http://images.novusbio.com/images/af346_human-bmpr-ia-alk-3-affinity-purified-polyclonal-ab-elisa-639201850089060174.jpg)
