BMP-15/GDF-9B Antibody (582703) [Alexa Fluor® 405]

• Applications: IHC
• Clone: 582703
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 405

BMP-15/GDF-9B Antibody (582703) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant mouse BMP‑15/GDF‑9B
  Gln268-Arg392
  Accession # Q9Z0L4
• Specificity: Detects mouse BMP‑15/GDF‑9B in direct ELISAs. In this format, no cross-reactivity with recombinant human BMP1.1, 2, 3, 3b, 4, 5, 6, 7, 8, 9, 10, 15, recombinant mouse BMP-3, 3b, 4, 5, 6, 7, 8b, 9, or 10 is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BMP-15/GDF-9B Antibody (582703) [Alexa Fluor® 405]

• BMP15
• BMP-15
• bone morphogenetic protein 15
• GDF-9B
• Growth/differentiation factor 9B
• ODG2
• POF4

Background

Bone morphogenetic protein 15 (BMP-15), also known as GDF-9B, is a member of the TGF-beta superfamily. Mature BMP-15 has three intrachain disulfide bands that form a cysteine-knot fold. It is secreted as a 34 kDa non-disulfide-linked homodimer and as a 37 kDa nondisulfide heterodimer with GDF-9. BMP-15 is a product of oocytes and promotes granulosa cell proliferation and stem cell factor secretion. Mature mouse BMP-15 shares 44% aa sequence identity with mature mouse GDF-9. It also shares 70% and 78% aa sequence identity with human and sheep BMP-15, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q9Z0L4()