BMP-15/GDF-9B Antibody (582703) [Alexa Fluor® 350]

• Reactivity: Mu
• Applications: IHC
• Clone: 582703
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 350

BMP-15/GDF-9B Antibody (582703) [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant mouse BMP‑15/GDF‑9B
  Gln268-Arg392
  Accession # Q9Z0L4
• Specificity: Detects mouse BMP‑15/GDF‑9B in direct ELISAs. In this format, no cross-reactivity with recombinant human BMP1.1, 2, 3, 3b, 4, 5, 6, 7, 8, 9, 10, 15, recombinant mouse BMP-3, 3b, 4, 5, 6, 7, 8b, 9, or 10 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BMP-15/GDF-9B Antibody (582703) [Alexa Fluor® 350]

• BMP15
• BMP-15
• bone morphogenetic protein 15
• GDF-9B
• Growth/differentiation factor 9B
• ODG2
• POF4

Background

Bone morphogenetic protein 15 (BMP-15), also known as GDF-9B, is a member of the TGF-beta superfamily. Mature BMP-15 has three intrachain disulfide bands that form a cysteine-knot fold. It is secreted as a 34 kDa non-disulfide-linked homodimer and as a 37 kDa nondisulfide heterodimer with GDF-9. BMP-15 is a product of oocytes and promotes granulosa cell proliferation and stem cell factor secretion. Mature mouse BMP-15 shares 44% aa sequence identity with mature mouse GDF-9. It also shares 70% and 78% aa sequence identity with human and sheep BMP-15, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.