Recombinant Human BMP-10 Protein

Product Discontinued

Recombinant Human BMP-10 Protein Summary

• Description: Recombinant bioactive protein for Human BMP-10
  
  

  Source:E. coli
  Amino Acid Sequence:(O95393)

• Preparation Method: Determined to be >98% pure by SDS-PAGE
• Details of Functionality: The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED50 is in the range of 0.3-3 ug/ml.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: BMP10
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 32 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Sterile filtered and lyophilized with no additives.
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute to a concentration of 0.1 - 1.0 mg/ml in H2O containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers

Alternate Names for Recombinant Human BMP-10 Protein

• BMP10
• BMP-10
• bone morphogenetic protein 10
• MGC126783

Background

BMPs (bone morphogenetic proteins) belong to the TGF-Beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-10 is essential for the proper development of the heart, but is not expressed until after cardiac patterning or looping are completed. Recombinant human BMP-10 is a 32 kDa disulfide-linked homodimer containing two 142 amino acid polypeptide chains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: BMP10