Recombinant Human Biliverdin Reductase B/BLVRB Protein

Product Discontinued

Recombinant Human Biliverdin Reductase B/BLVRB Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 1-206 of Human Biliverdin Reductase B/BLVRB
  
  

  Source: E.coli

  Amino Acid Sequence: MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: BLVRB
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 22.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris buffer (pH 8.5), 10% glycerol, 1 mM DTT
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95% pure by SDS-PAGE

Alternate Names for Recombinant Human Biliverdin Reductase B/BLVRB Protein

• biliverdin reductase B (flavin reductase (NADPH))
• Biliverdin Reductase B
• Biliverdin-IX beta-reductase
• BLVRB
• BVRB
• BVR-B
• EC 1.3.1.24
• EC 1.5.1.30
• flavin reductase (NADPH)
• flavin reductase
• FLR
• FLRBVRB
• FR
• GHBP
• Green heme-binding protein
• MGC117413
• NADPH-dependent diaphorase
• NADPH-flavin reductase
• SDR43U1
• short chain dehydrogenase/reductase family 43U, member 1

Background

Biliverdin reductase B (BLVRB) is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: BLVRB