beta-Galactosidase-1/GLB1 Antibody (OTI1C9) [DyLight 550]

• Reactivity: Hu, Ca, Pm
• Applications: WB, IHC
• Clone: OTI1C9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

beta-Galactosidase-1/GLB1 Antibody (OTI1C9) [DyLight 550] Summary

• Immunogen: Full length recombinant protein of human beta-Galactosidase-1/GLB1 (NP_001073279) produced in HEK293T cells.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: GLB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for beta-Galactosidase-1/GLB1 Antibody (OTI1C9) [DyLight 550]

• Acid beta-galactosidase
• beta-galactosidase
• betaGalactosidase1
• beta-Galactosidase-1
• EBP
• EC 3.2.1.23
• elastin receptor 1 (67kD)
• Elastin receptor 1
• elastin receptor 1, 67kDa
• ELNR1
• galactosidase, beta 1
• GLB1
• Lactase
• MPS4B

Background

The GLB1 gene encodes beta-galactosidase-1 (EC 3.2.1.23), a lysosomal hydrolase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates (Yoshida et al., 1991 [PubMed 1907800]). Beta-galactosidase also occurs in a complex with neuraminidase (NEU1; MIM 608272) and protective protein/cathepsin A (PPCA; MIM 256540), which is a component of certain cell surface receptors (Hinek, 1996 [PubMed 8922281]). See also galactosylceramidase (GALC; MIM 606890) (EC 3.2.1.46), a genetically distinct beta-galactosidase that is involved in the catabolism of other lipid compounds.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GLB1