beta 2-Microglobulin Antibody (SPM617) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
SPM617
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

beta 2-Microglobulin Antibody (SPM617) [Janelia Fluor® 646] Summary

Immunogen
Full length recombinant human B2M protein
Localization
Cell Surface and Extracellular (Secreted)
Marker
Renal Failure & Tumor Marker
Specificity
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
B2M
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for beta 2-Microglobulin Antibody (SPM617) [Janelia Fluor® 646]

  • B2M
  • beta 2Microglobulin
  • beta 2-Microglobulin
  • beta chain of MHC class I molecules
  • beta-2-microglobin
  • beta-2-microglobulin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for beta 2-Microglobulin Antibody (NBP2-47703JF646) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47703AF350
Alexa Fluor 405 NBP2-47703AF405
Alexa Fluor 488 NBP2-47703AF488
Alexa Fluor 532 NBP2-47703AF532
Alexa Fluor 594 NBP2-47703AF594
Alexa Fluor 647 NBP2-47703AF647
Alexa Fluor 700 NBP2-47703AF700
Alexa Fluor 750 NBP2-47703AF750
Allophycocyanin NBP2-47703APC
Allophycocyanin/Cy7 NBP2-47703APCCY7
Biotin NBP2-47703B
DyLight 350 NBP2-47703UV
DyLight 405 NBP2-47703V
DyLight 488 NBP2-47703G
DyLight 550 NBP2-47703R
DyLight 594 NBP2-47703DL594
DyLight 650 NBP2-47703C
DyLight 680 NBP2-47703FR
DyLight 755 NBP2-47703IR
FITC NBP2-47703F
HRP NBP2-47703H
Janelia Fluor 549 NBP2-47703JF549
Janelia Fluor 646 NBP2-47703JF646
PE NBP2-47703PE
PE/Atto594 NBP2-47703PEATT594
PE/Cy5.5 NBP2-47703PECY55
PE/Cy7 NBP2-47703PECY7
PerCP NBP2-47703PCP

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Bioinformatics

Gene Symbol B2M
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