BCCIP Antibody [DyLight 650]

• Reactivity: Hu
• Applications: IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 650

BCCIP Antibody [DyLight 650] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human BRCA2 and CDKN1A interacting protein using the numbering given in entry NP_510868.1 (GeneID 56647).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BCCIP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BCCIP Antibody [DyLight 650]

• BCCIPalpha
• BRCA2 and CDKN1A interacting protein
• BRCA2 and CDKN1A-interacting protein
• BRCA2 and Cip1/p21 interacting protein
• cdk inhibitor p21 binding protein
• P21- and CDK-associated protein 1
• Protein TOK-1
• TOK-1
• TOK-1alpha
• TOK1BCCIPbeta
• TOK-1beta

Background

BCCIP (BRCA2 and CDKN1A interacting protein) was isolated as a BRCA2 and p21 interacting protein. Downregulation of BCCIP results in chromosome instability and incomplete cytokinesis indicating a role in DNA damage. Additionally, BCCIP is critical for BRCA2- and Rad51-dependent homologous recombinational repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BCCIP