BCCIP Antibody

Images

 
Immunohistochemistry: BCCIP Antibody [NBP1-22994] - FPE section of human colon carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit.
Immunohistochemistry-Paraffin: BCCIP Antibody [NBP1-22994] - Human prostate carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml).
Immunoprecipitation: BCCIP Antibody [NBP1-22994] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-BCCIP antibody used for IP at 3 mcg/mg lysate. BCCIP was ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P, IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

BCCIP Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human BRCA2 and CDKN1A interacting protein using the numbering given in entry NP_510868.1 (GeneID 56647).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BCCIP
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate
Application Notes
It is not recommended for western analysis.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BCCIP Antibody

  • BCCIPalpha
  • BRCA2 and CDKN1A interacting protein
  • BRCA2 and CDKN1A-interacting protein
  • BRCA2 and Cip1/p21 interacting protein
  • cdk inhibitor p21 binding protein
  • P21- and CDK-associated protein 1
  • Protein TOK-1
  • TOK-1
  • TOK-1alpha
  • TOK1BCCIPbeta
  • TOK-1beta

Background

BCCIP (BRCA2 and CDKN1A interacting protein) was isolated as a BRCA2 and p21 interacting protein. Downregulation of BCCIP results in chromosome instability and incomplete cytokinesis indicating a role in DNA damage. Additionally, BCCIP is critical for BRCA2- and Rad51-dependent homologous recombinational repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BCCIP
Entrez
Uniprot