BCAS1 Antibody

Images

 
Western Blot: BCAS1 Antibody [NBP1-77123] - human lung tissue lysate with BCAS1 antibody at 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: BCAS1 Antibody [NBP1-77123] - Human Breast Carcinoma cells with BCAS1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: BCAS1 Antibody [NBP1-77123] - Human breast carcinoma with BCAS1 antibody at 5 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

BCAS1 Antibody Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human BCAS1. The immunogen is located within amino acids 460 - 510 of BCAS1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BCAS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL.
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Positive Control
BCAS1 Antibody (NBP1-77123)
Control Peptide
BCAS1 Peptide (NBP1-77123PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BCAS1 Antibody

  • breast carcinoma amplified sequence 1
  • breast carcinoma-amplified sequence 1
  • NABC1AIBC1Amplified and overexpressed in breast cancer
  • Novel amplified in breast cancer 1

Background

BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein; BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for BCAS1 Antibody (NBP1-77123) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for BCAS1 Antibody (NBP1-77123)

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Bioinformatics

Gene Symbol BCAS1
Uniprot