BAI1 Antibody

Immunohistochemistry-Paraffin: BAI1 Antibody [NLS989] - Anti-BAI1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: BAI1 Antibody [NLS989] - Analysis of anti-BAI1 antibody with human brain, neurons.

Immunohistochemistry-Paraffin: BAI1 Antibody [NLS989] - Anti-BAI1 antibody IHC of human prostate, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Discontinued

BAI1 Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from C-terminus of human BAI1.
• Specificity: Human BAI1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Opossum (100%), Zebrafish (94%), Xenopus (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADGRB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 14 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for BAI1 Antibody

• BAI1
• brain-specific angiogenesis inhibitor 1
• FLJ41988
• GDAIF

Background

BAI1 is an Orphan-B GPCR with an unknown ligand. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis, and a growth suppressor of glioblastoma. Along with BAI1, there are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3, which have similar tissue specificities and structures. However, only BAI1 is transcriptionally regulated by p53. Loss of BAI1 expression has been implicated in glioblastoma. BAI1 expression has been reported primarily in brain, but it is also found in colon, lung, esophagus, and uterus. ESTs have been isolated from brain, lung, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADGRB1
• Entrez:
  • 575(Human)