Recombinant Human BAFFR/TNFRSF13C Protein

Product Discontinued

Recombinant Human BAFFR/TNFRSF13C Protein Summary

• Description: Recombinant bioactive protein containing 76 amino acids for Human BAFF Receptor
  
  

  Source:E. coli
  Amino Acid Sequence:(Q96RJ3)

• Details of Functionality: Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is typically 1-5 ug/ml in the presence of 1 ug/ml human soluble BAFF.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: TNFRSF13C
• Purity: >95%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 7.7 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Sterile filtered and lyophilized from a solution containing 20 mM phosphate buffer, pH 8.0, and 500 mM NaCl.
• Concentration: Lyoph
• Purity: >95%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in sterile H2O to a concentration of 0.1 - 1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4C for 1 week or -20C for long-term storage.

Alternate Names for Recombinant Human BAFFR/TNFRSF13C Protein

• BAFF R
• BAFFR
• BAFFR;BAFF-R;BROMIX;CD268;CVID4;prolixin;Tumor necrosis factor receptor superfamily member 13C
• BR3
• CD268
• TNFRSF13C

Background

BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extraCellular portion of the full BAFFR protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TNFRSF13C