B3GALTL Antibody

Images

 
Western Blot: B3GALTL Antibody [NBP1-32787] - Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE, antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: B3GALTL Antibody [NBP1-32787] - Paraffin-embedded NCIN87 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

B3GALTL Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human B3GALTL. The exact sequence is proprietary.
Localization
Endoplasmic reticulum membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
B3GALTL
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (80%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for B3GALTL Antibody

  • B3GALTL
  • B3GLCT
  • B3Glc-T
  • B3GTL
  • B3GTLbeta3Glc-T
  • beta 1,3-galactosyltransferase-like
  • beta 3-glycosyltransferase-like
  • beta-1,3-glucosyltransferase
  • Beta3Glc-T
  • beta-3-glycosyltransferase-like
  • EC 2.4.1.-
  • Gal-T
  • UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like

Background

B3GALTL is a beta-1,3-glucosyltransferase involved in the synthesis of the unusual O-linked disaccharide glucosyl-beta-1,3-fucose-O- found on the thrombospondin (see THBS1; MIM 188060) type-1 repeats (TSRs) of many biologically important proteins. Biosynthesis of glucosyl-beta-1,3-fucose-O- is initiated by protein O-fucosyltransferase-2 (POFUT2; MIM 610249), which attaches the fucosyl residue to a serine or threonine within the TSR. B3GALTL subsequently transfers the glucose onto TSR-fucose (Hess et al., 2008 [PubMed 18199743]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol B3GALTL
Entrez