B3GALTL Products

Description

B3GALTL is a beta-1,3-glucosyltransferase involved in the synthesis of the unusual O-linked disaccharide glucosyl-beta-1,3-fucose-O- found on the thrombospondin (see THBS1; MIM 188060) type-1 repeats (TSRs) of many biologically important proteins. Biosynthesis of glucosyl-beta-1,3-fucose-O- is initiated by protein O-fucosyltransferase-2 (POFUT2; MIM 610249), which attaches the fucosyl residue to a serine or threonine within the TSR. B3GALTL subsequently transfers the glucose onto TSR-fucose (Hess et al., 2008 [PubMed 18199743]).[supplied by OMIM]

Bioinformatics

Entrez	145173 Human
Uniprot	NM_194318 Human NP_919299 Human Q6Y288 Human
Product By Gene ID	145173
Alternate Names	B3GLCT B3Glc-T B3GTLbeta3Glc-T beta 1,3-galactosyltransferase-like beta 3-glycosyltransferase-like beta-1,3-glucosyltransferase Beta3Glc-T beta-3-glycosyltransferase-like Beta-3-glycosyltransferase-like EC 2.4.1.- Gal-T UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like