Axl Antibody (10E7)

Product Discontinued

Axl Antibody (10E7) Summary

• Immunogen: Recombinant Mouse Axl extracellular domain
• Specificity: This recognizes mouse Axl in western blot. It has no cross reactivity to rmMer or rmDtk.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: AXL
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 0.2 um filtered PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for Axl Antibody (10E7)

• AI323647
• ARK
• AXL oncogene
• AXL receptor tyrosine kinase
• AXL transforming sequence/gene
• Axl
• EC 2.7.10
• EC 2.7.10.1
• JTK11
• Tyro7
• tyrosine-protein kinase receptor UFO
• UFO
• UFOoncogene AXL

Background

Axl is a receptor tyrosine kinase (RTK) that binds the ligand Gas6 (growth-arrest specific gene). It is part of a sub-family of RTKs that includes Axl, SKY and MER. The Axl gene was first identified as a transforming cDNA isolated from patients with chronic myelogenous leukemia. Axl-Gas6 signaling is implicated in cellular responses such as cell survival, proliferation, migration, and adhesion, and it may be involved in cancer progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AXL