ATR Antibody (2B5) [DyLight 488]

Product Discontinued

ATR Antibody (2B5) [DyLight 488] Summary

• Immunogen: Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ATR
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ATR Antibody (2B5) [DyLight 488]

• ataxia telangiectasia and Rad3 related
• Ataxia telangiectasia and Rad3-related protein
• ATR
• EC 2.7.11.1
• FRAP-related protein 1
• FRP1
• FRP1FRAP-related protein-1
• MEC1
• protein kinase ATR
• Rad3 related protein
• SCKL1
• SCKLMEC1, mitosis entry checkpoint 1, homolog
• serine/threonine-protein kinase ATR

Background

Ataxia Telangiectasia Mutated (ATM) and Rad3- related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATR