ATP6V1G2 Antibody - BSA Free

Immunohistochemistry-Paraffin: ATP6V1G2 Antibody [NBP3-17121] - Staining of human cerebral cortex shows high expression.

Immunohistochemistry-Paraffin: ATP6V1G2 Antibody [NBP3-17121] - Analysis in human cerebral cortex and duodenum tissues using Anti-ATP6V1G2 antibody. Corresponding ATP6V1G2 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: ATP6V1G2 Antibody [NBP3-17121] - Staining of human duodenum shows low expression as expected.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ATP6V1G2 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: NLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVC
• Predicted Species: Mouse (100%), Rat (97%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATP6V1G2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.2, 40% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ATP6V1G2 Antibody - BSA Free

• ATP6G2
• ATPase, H+ transporting, lysosomal (vacuolar proton pump)
• ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 2
• ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
• Em:AC004181.3
• subunit G2
• vacuolar ATP synthase subunit G 2
• vacuolar proton pump G subunit 2
• Vacuolar proton pump subunit G 2
• V-ATPase 13 kDa subunit 2
• V-ATPase subunit G 2
• Vma10
• V-type proton ATPase subunit G 2

Background

ATP6V1G2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATP6V1G2