ATG9B Antibody

Product Discontinued

ATG9B Antibody Summary

• Immunogen: A synthetic peptide as a part of mouse autophagy-related protein 9B (ATG9B, APG9L2, NOS3AS) conjugated to an immunogenic carrier protein has been used as the immunogen.
• Specificity: ATG9B.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATG9B
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200-1:2000
  • Western Blot 1:200-1:2000

Reactivity Notes

Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute in 150 ul of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Alternate Names for ATG9B Antibody

• APG9L2APG9-like 2
• ATG9 autophagy related 9 homolog B (S. cerevisiae)
• autophagy-related protein 9B
• endothelial nitric oxide synthase antisense
• nitric oxide synthase 3 antisense
• Nitric oxide synthase 3-overlapping antisense gene protein
• NOS3ASautophagy 9-like 2 protein
• Protein sONE
• SONEFLJ14885

Background

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.; FUNCTION: Plays a role in autophagy.; SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.; INDUCTION: By hypoxia, leading to inhibit NOS3 expression.;

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for ATG9B Antibody (NB110-74836). (Showing 1 - 2 of 2 FAQ).

1. How much is the molecular weight of ATG9B protein?
   • The predicted molecular weight of ATG9B protein is 101kDa
2. Is this ATG9b antibody (NB110-74836) the same as the (discontinued?) R-144-100? Or are they different products?
   • Our product NB110-74836 is a different product than our discontinued product R-144-100. NB110-74836 is made against mouse autophagy-related protein 9B (ATG9B) and R-144-100 was made against human autophagy-related protein 9B (ATG9B). We have been recommending NBP1-77169 as a replacement product to R-144-100.

Bioinformatics

• Gene Symbol: ATG9B
• Entrez:
  • 213948(Mouse)
  • 499973(Rat)
• Uniprot:
  • Q6EBV9(Mouse)