Atad5 Antibody [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 488

Atad5 Antibody [Alexa Fluor™ Plus 488] Summary

• Immunogen: A synthetic peptide corresponding to amino acids 63-76 of Human Elg 1.
• Specificity: BLAST analysis of the immunogen suggest full to partial reactivity with several hypothetical proteins. This is not unexpected for such a novel protein. The following proteins should be considered to be highly homologous to Elg1 when using this antibody: human chromosome fragility associated gene 1 (NP_079133), hypothetical dog protein FLJ12735 (XP_548276), hypothetical chimpanzee protein FLJ12735 (XP_511388), and a hypothetical human protein of 1224 residues (CAH10412). All show 100% homology to the immunogen. Reactivity against homologues from other sources is not known.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATAD5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

BLAST analysis of the immunogen suggest full to partial reactivity with several hypothetical proteins. This is not unexpected for such a novel protein. The following proteins should be considered to be highly homologous to Elg1 when using this antibody: human chromosome fragility associated gene 1 (NP_079133), hypothetical dog protein FLJ12735 (XP_548276), hypothetical chimpanzee protein FLJ12735 (XP_511388), and a hypothetical human protein of 1224 residues (CAH10412). All show 100% homology to the immunogen. Reactivity against homologues from other sources is not known.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Atad5 Antibody [Alexa Fluor™ Plus 488]

• Atad5
• ATPase family AAA domain-containing protein 5
• ATPase family, AAA domain containing 5
• C17orf41
• chromosome fragility associated gene 1
• Chromosome fragility-associated gene 1 protein
• ELG1
• enhanced level of genomic instability 1 homolog
• FLJ12735
• FRAG1
• FRAG1chromosome 17 open reading frame 41

Background

ATAD5/FRAG1 has been identified as a homolog of a subunit of RFC (replication factor C) and has been shown to be down-regulated in response to replicative stress. ATAD5/FRAG1 may play a role in the surveillance of DNA damage and the cell's decision to survive or activate apoptosis. ATAD5/FRAG1 is also known as ATPase family AAA domain containing 5, and FLJ12735.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATAD5