Arylsulfatase B/ARSB Antibody (708401) [Janelia Fluor® 646]

Product Discontinued

Arylsulfatase B/ARSB Antibody (708401) [Janelia Fluor® 646] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Arylsulfatase B/ARSB
  Ser37-Met533
  Accession # P15848
• Specificity: Detects human Arylsulfatase B/ARSB in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) ARSA, rhARSJ, or recombinant mouse ARSG is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ARSB
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Arylsulfatase B/ARSB Antibody (708401) [Janelia Fluor® 646]

• ARSB
• Arylsulfatase B
• ASB
• EC 3.1.6.12
• G4S
• MPS6
• N-acetylgalactosamine-4-sulfatase

Background

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARSB