ARHGEF7 Antibody - BSA Free

Western Blot: ARHGEF7 Antibody [NBP2-92602] - Analysis of extracts of various cell lines, using ARHGEF7 at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ARHGEF7 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ARHGEF7 Antibody - BSA Free (NBP2-92602) is a polyclonal antibody validated for use in WB. Anti-ARHGEF7 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7 (NP_001106984.1). MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARHGEF7
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ARHGEF7 Antibody - BSA Free

• Beta-Pix
• COOL1COOL-1
• DKFZp686C12170
• DKFZp761K1021
• guanine nucleotide exchange factor 7
• KIAA0142KIAA0412
• Nbla10314
• P50
• P50BP
• P85
• P85COOL1
• P85SPRBETA-PIX
• PAK3
• PAK3BP
• PIXBPAK-interacting exchange factor beta
• Rho guanine nucleotide exchange factor (GEF) 7
• rho guanine nucleotide exchange factor 7
• SH3 domain-containing proline-rich protein

Background

ARHGEF7, also known as Rho guanine nucleotide exchange factor 7, contains many isoforms that are 90 kDa, 87 kDa, 84 kDa, 82 kDa, 73 kDa, and 70 kDa, and is involved in apoptosis regulation, cell migration, and cell spreading. Current disease research is being conducted on ARHGEF7 and its relation to Borjeson-Forssmann-Lehmann Syndrome, t-cell leukemia, breast cancer, Wiskott-Aldrich Syndrome, insulin resistance, neuronitis, pancreatitis, leukemia, neuroblastoma, insulin resistance, adenocarcinoma, and lung cancer. This protein is linked to the GPCR pathway and the RhoA pathway, and it interacts with SCRIB, CBL, GIT1, PAK1, and CBLB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ARHGEF7 Antibody (NBP2-92602)(1)

Publication using NBP2-92602

• Jeon Y, Shin YK, Kim H et al. ?Pix Guanine Nucleotide Exchange Factor Regulates Regeneration of Injured Peripheral Axons Int J Mol Sci 2023-09-20 [PMID: 37762659]

Bioinformatics

• Gene Symbol: ARHGEF7