ARHGEF11 Antibody

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Western Blot: ARHGEF11 Antibody [NBP1-06553] - Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. NBP1-06553 used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ...read more
Immunohistochemistry: ARHGEF11 Antibody [NBP1-06553] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- PDZ-RhoGEF used at a dilution of 1:200 (1ug/ml). Detection: DAB

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

       

Order Details

ARHGEF11 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1472 and 1522 of human PDZ-RhoGEF using the numbering given in entry NP_055599.1 (GeneID 9826).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ARHGEF11
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry-Paraffin 1:100-1:500
  • Immunoprecipitation 2-5 ug/mg
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ARHGEF11 Antibody

  • DKFZp667F1223
  • glutamate transporter EAAT4-associated protein 48
  • GTRAP48
  • KIAA0380rho guanine nucleotide exchange factor 11
  • PDZ-RHOGEF
  • Rho guanine exchange factor (GEF) 11
  • Rho guanine nucleotide exchange factor (GEF) 11
  • RhoA-specific guanine nucleotide exchange factor
  • RhoGEF glutamate transport modulator

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ARHGEF11
Entrez
Uniprot