ARAP1 Antibody (ARAP1-2) - BSA Free Summary
Immunogen |
His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1 |
Specificity |
The ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
ARAP1 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/Immunofluorescence 1:10-1:2000
- Immunoprecipitation 1:50
- Western Blot 2 ug/ml
|
Theoretical MW |
160 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
PBS (pH 7.4) |
Preservative |
15mM Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Protein A purified |
Alternate Names for ARAP1 Antibody (ARAP1-2) - BSA Free
Background
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for ARAP1 Antibody (NB110-68801) (0)
Secondary Antibodies
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Isotype Controls
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