APXL Antibody

Images

 
Western Blot: APXL Antibody [NBP2-15437] - Sample (30 ug of whole cell lysate) A: Hep G2 5% SDS PAGE, antibody diluted at 1:500.
Immunohistochemistry-Paraffin: APXL Antibody [NBP2-15437] - Paraffin-embedded Brain, cortex, using antibody 10 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, PmSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

APXL Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human APXL. The exact sequence is proprietary.
Localization
Apical cell membrane (By similarity); Cell junction; tight junction (By similarity); Cytoplasm; cytoskeleton (By similarity)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SHROOM2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
176 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%) and Rat (85%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for APXL Antibody

  • apical protein, Xenopus laevis-like
  • apical protein-like (Xenopus laevis)
  • Apical-like protein
  • APX homolog of Xenopus
  • APXLHSAPXL
  • DKFZp781J074
  • FLJ39277
  • Protein APXL
  • protein Shroom2
  • shroom family member 2

Background

The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Video Protocols

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Bioinformatics

Gene Symbol SHROOM2
Uniprot