APBB2 Antibody - BSA Free

Western Blot:[NBP3-30255]-Detection of human APBB2 by western blot and immunoprecipitation. Samples: Whole cell lysate from HEK293T , HeLa and Jurkat cells. Antibodies: Affinity purified rabbit anti-APBB2 antibody used for WB at 0. 4 µg/ml and 1 µg/ml and used for IP at 6 µg/mg lysate. APBB2 was also immunoprecipitated by rabbit anti-APBB2 antibody , which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes and 30 seconds.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

APBB2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit APBB2 Antibody - BSA Free (NBP3-30255) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Between 708 and 758
• Assay Type: [Assay Type]
• Sample Volume: [Sample Volume]
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: APBB2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-citrate/phosphate buffer, pH 7 to 8
• Preservative: 0.09% Sodium Azide
• Purity: Affinity purified

Alternate Names for APBB2 Antibody - BSA Free

• amyloid beta (A4) precursor protein-binding, family B, member 2
• amyloid beta A4 precursor protein-binding family B member 2
• DKFZp434E033
• FE65L1FE65LMGC35575
• Fe65-like 1
• Protein Fe65-like 1

Background

Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the beta-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down's syndrome and a variety of neurological disorders, including Alzheimer's disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid ®/A4 protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane- bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APBB2