APBB2 Products

Antibodies
APBB2 Antibody
APBB2 Antibody
NBP1-84700
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
APBB2 Antibody
APBB2 Antibody
NBP2-15421
Species: Hu, Mouse
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
APBB2 Antibody (2D8)
APBB2 Antibody (2D8)
H00000323-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Proteins
APBB2 Partial Recombinant Pro ...
APBB2 Partial Recombinant Protein
H00000323-Q01
Species: Hu
Applications: WB, ELISA, PA
APBB2 Recombinant Protein Ant ...
APBB2 Recombinant Protein Antigen
NBP1-84700PEP
Species: Hu
Applications: AC
RNAi
APBB2 RNAi
APBB2 RNAi
H00000323-R01
Species: Hu

Description

Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the beta-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down's syndrome and a variety of neurological disorders, including Alzheimer's disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid ®/A4 protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane- bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 323
Alternate Names
  • Fe65-like 1
  • DKFZp434E033
  • amyloid beta A4 precursor protein-binding family B member 2
  • Protein Fe65-like 1
  • FE65L1FE65LMGC35575
  • amyloid beta (A4) precursor protein-binding, family B, member 2

Research Areas for APBB2

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Phospho-Specific

PTMs for APBB2

Learn more about PTMs related to APBB2.

Cleavage
Phosphorylation

Bioinformatics Tool for APBB2

Discover related pathways, diseases and genes to APBB2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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