Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu
Applications: AC
Description
APBA1 is encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq]
Bioinformatics
Entrez |
Mouse Human Rat |
Uniprot |
Human Human |
Product By Gene ID |
320 |
Alternate Names |
- Adapter protein X11alpha
- amyloid beta (A4) precursor protein-binding, family A, member 1
- amyloid beta A4 precursor protein-binding family A member 1
- D9S411Eadaptor protein X11alpha
- LIN10
- Mint-1
- mint-1
- MINT1amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
- Neuronal Munc18-1-interacting protein 1
- Neuron-specific X11 protein
- phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
- UROP11
- X11A
- X11X11ALPHA
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