ANKRD11 Antibody - BSA Free

Western Blot: ANKRD11 Antibody - BSA Free [NBP3-48161] - BxPC-3 cells were subjected to SDS PAGE followed by western blot with (ANKRD11 antibody) at dilution of 1:500

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ANKRD11 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ANKRD11 Antibody - BSA Free (NBP3-48161) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: ankyrin repeat domain 11. (Uniprot# Q6UB99)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ANKRD11
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:200-1:2000
• Theoretical MW: 160 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ANKRD11 Antibody - BSA Free

• ANCO-1
• ANCO1ankyrin repeat domain-containing protein 11
• ankyrin repeat domain 11
• Ankyrin repeat-containing cofactor 1
• ankyrin repeat-containing protein 11
• LZ16
• nasopharyngeal carcinoma susceptibility protein
• T13

Background

Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 22-24 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases; most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ANKRD11