AMPD3 Antibody (AMPD3/901) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC-P
Clone
AMPD3/901
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

AMPD3 Antibody (AMPD3/901) [DyLight 550] Summary

Immunogen
Recombinant full-length human AMDP3 protein
Localization
Cell Surface
Marker
Erythroid Marker
Specificity
It recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
AMPD3
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody shomld be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for AMPD3 Antibody (AMPD3/901) [DyLight 550]

  • adenosine monophosphate deaminase (isoform E)
  • adenosine monophosphate deaminase 3
  • AMP aminohydrolase
  • AMP deaminase 3
  • AMP deaminase isoform E
  • EC 3.5.4.6
  • Erythrocyte AMP deaminase
  • erythrocyte type AMP deaminase
  • erythrocyte-specific AMP deaminase
  • myoadenylate deaminase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AMPD3