AMPD3 Antibody (AMPD3/901) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
AMPD3/901
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

AMPD3 Antibody (AMPD3/901) [Janelia Fluor® 646] Summary

Immunogen
Recombinant full-length human AMDP3 protein
Localization
Cell Surface
Marker
Erythroid Marker
Specificity
It recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
AMPD3
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for AMPD3 Antibody (AMPD3/901) [Janelia Fluor® 646]

  • adenosine monophosphate deaminase (isoform E)
  • adenosine monophosphate deaminase 3
  • AMP aminohydrolase
  • AMP deaminase 3
  • AMP deaminase isoform E
  • EC 3.5.4.6
  • Erythrocyte AMP deaminase
  • erythrocyte type AMP deaminase
  • erythrocyte-specific AMP deaminase
  • myoadenylate deaminase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47691AF350
Alexa Fluor 405 NBP2-47691AF405
Alexa Fluor 488 NBP2-47691AF488
Alexa Fluor 532 NBP2-47691AF532
Alexa Fluor 594 NBP2-47691AF594
Alexa Fluor 647 NBP2-47691AF647
Alexa Fluor 700 NBP2-47691AF700
Alexa Fluor 750 NBP2-47691AF750
Allophycocyanin NBP2-47691APC
Biotin NBP2-47691B
DyLight 350 NBP2-47691UV
DyLight 405 NBP2-47691V
DyLight 488 NBP2-47691G
DyLight 550 NBP2-47691R
DyLight 594 NBP2-47691DL594
DyLight 650 NBP2-47691C
DyLight 680 NBP2-47691FR
DyLight 755 NBP2-47691IR
FITC NBP2-47691F
HRP NBP2-47691H
Janelia Fluor 549 NBP2-47691JF549
Janelia Fluor 646 NBP2-47691JF646
PE NBP2-47691PE
PerCP NBP2-47691PCP

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