Aminopeptidase LRAP/ERAP2 Antibody [DyLight 550]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 550

Aminopeptidase LRAP/ERAP2 Antibody [DyLight 550] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Aminopeptidase LRAP/ERAP2
  Ala56-Thr960
  Accession # Q6P179
• Specificity: Detects human Aminopeptidase LRAP/ERAP2 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ERAP2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Aminopeptidase LRAP/ERAP2 Antibody [DyLight 550]

• Aminopeptidase LRAP
• EC 3.4.11
• EC 3.4.11.3
• endoplasmic reticulum aminopeptidase 2
• ERAP2
• FLJ23633
• FLJ23701
• FLJ23807
• Leukocyte-derived arginine aminopeptidase
• LRAPL-RAPEC 3.4.11.-

Background

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2; MIM 190470) (Tanioka et al., 2003 [PubMed 12799365]).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERAP2