alpha-Fetoprotein/AFP Native Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IA
Concentration
1 mg/ml

Order Details

alpha-Fetoprotein/AFP Native Protein Summary

Description
Purified human alpha fetoprotein.

Source:Human cord serum

Amino Acid Sequence:UniProt P02771

Source
Human serum
Protein/Peptide Type
Native Protein
Gene
AFP
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • Immunoassay
Theoretical MW
63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
TBS
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
>95%, by SDS-PAGE

Alternate Names for alpha-Fetoprotein/AFP Native Protein

  • AFP
  • Alpha-1-fetoprotein
  • alpha-fetoglobulin
  • alpha-Fetoprotein
  • DSCAM2
  • FETA
  • HP
  • HPAFP

Background

Alpha 1 Fetoprotein encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AFP