alpha-Fetoprotein/AFP Products

Description

Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.

Bioinformatics

Entrez	174 Human
Product By Gene ID	174
Alternate Names	AFP Alpha-1-fetoprotein alpha-fetoglobulin alpha-Fetoprotein DSCAM2 FETA HP HPAFP

Research Areas for alpha-Fetoprotein/AFP

Find related products by research area and learn more about each of the different research areas below.

Cancer
Stem Cell Markers