alpha-Fetoprotein/AFP Products

Description

Alpha 1 Fetoprotein encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Bioinformatics

Entrez	11576 Mouse 174 Human 24177 Rat
Uniprot	AAB58754.1 Human AAH27881 Human AAH27881.1 Human NM_001134 Human NP_001125 Human NP_001125 Human NP_001125.1 Human P02771 Human P02771 Human
Product By Gene ID	174
Alternate Names	alpha-1-fetoprotein Alpha-1-fetoprotein alpha-fetoglobulin Alpha-fetoglobulin alpha-fetoprotein FETA HP HPAFP

Research Areas for alpha-Fetoprotein/AFP

Find related products by research area and learn more about each of the different research areas below.

Cancer
GPCR
Stem Cell Markers