alpha-Fetoprotein/AFP Antibody (MBS-12) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P
Clone
MBS-12
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

alpha-Fetoprotein/AFP Antibody (MBS-12) [DyLight 680] Summary

Immunogen
Recombinant full-length human Alpha fetoprotein
Localization
Cytoplasmic
Marker
Hepatocellular/Germ Cell Tumor Marker
Specificity
It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. The yolk sac and the liver produce AFP during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spinal bifida and anencephaly.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
AFP
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for alpha-Fetoprotein/AFP Antibody (MBS-12) [DyLight 680]

  • AFP
  • Alpha-1-fetoprotein
  • alpha-fetoglobulin
  • alpha-Fetoprotein
  • DSCAM2
  • FETA
  • HP
  • HPAFP

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-48015AF350
Alexa Fluor 405 NBP2-48015AF405
Alexa Fluor 488 NBP2-48015AF488
Alexa Fluor 532 NBP2-48015AF532
Alexa Fluor 594 NBP2-48015AF594
Alexa Fluor 647 NBP2-48015AF647
Alexa Fluor 700 NBP2-48015AF700
Alexa Fluor 750 NBP2-48015AF750
Allophycocyanin NBP2-48015APC
Biotin NBP2-48015B
DyLight 350 NBP2-48015UV
DyLight 405 NBP2-48015V
DyLight 488 NBP2-48015G
DyLight 550 NBP2-48015R
DyLight 594 NBP2-48015DL594
DyLight 650 NBP2-48015C
DyLight 680 NBP2-48015FR
DyLight 755 NBP2-48015IR
FITC NBP2-48015F
HRP NBP2-48015H
Janelia Fluor 549 NBP2-48015JF549
Janelia Fluor 646 NBP2-48015JF646
PE NBP2-48015PE
PerCP NBP2-48015PCP

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Bioinformatics Tool for alpha-Fetoprotein/AFP Antibody (NBP2-48015FR)

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Bioinformatics

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