alpha Adaptin Antibody (SR1044) - BSA Free

Western Blot: alpha Adaptin Antibody (SR1044) [NBP3-21875] - Western blot analysis using NBP3-21875 in A431 cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, IHC
• Clone: SR1044
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

alpha Adaptin Antibody (SR1044) - BSA Free Summary

• Description: Novus Biologicals Rabbit alpha Adaptin Antibody (SR1044) - BSA Free (NBP3-21875) is a recombinant monoclonal antibody validated for use in IHC, WB, Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human alpha Adaptin (Uniprot #: O95782)
• Specificity: Detects endogenous levels of total alpha Adaptin
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: AP2A1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:100
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 108 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for alpha Adaptin Antibody (SR1044) - BSA Free

• 100 kDa coated vesicle protein A
• Adapter-related protein complex 2 alpha-1 subunit
• Adaptor protein complex AP-2 subunit alpha-1
• adaptor-related protein complex 2, alpha 1 subunit
• ADTAAAP2-ALPHA
• alpha1-adaptin
• Alpha-adaptin A
• AP-2 complex subunit alpha-1
• CLAPA1adaptin, alpha A
• Clathrin assembly protein complex 2 alpha-A large chain
• clathrin-associated/assembly/adaptor protein, large, alpha 1
• Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit

Background

AP2A1, also known as AP-2 complex subunit alpha-1, contains a 208 kDa and a 105 kDa isoform, and is involved in protein transport, vesicle formation, and clathrin-dependent endocytosis. Current research is being conducted on the relationship between AP2A1 and a variety of diseases and disorders, including seminoma, neuronitis, Huntington's disease, malaria, myeloid leukemia, carcinoma, gout, immunodeficiency, pancreatic cancer, prostatitis, prostate carcinoma, cholesterol, breast cancer, leukemia, and pancreatitis. AP2A1 is associated with Clathrin-dependent protein traffic, CTLA4 Signaling, p38 Signaling, the EGFR1 Signaling Pathway, the Synaptic Vesicle Pathway, the Arf1 pathway, and L1CAM interactions. The protein interacts with HIP1, TOE1, SMAD9, NUMB, and GRB2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AP2A1