ALK-1 Antibody (SR2004) - BSA Free

Western Blot: ALK-1 Antibody (SR2004) [NBP3-21752] - Western blot analysis using NBP3-21752 in (1) Jurkat cell lysate; (2) Mouse kidney lysate; (3) Rat kidney lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: SR2004
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ALK-1 Antibody (SR2004) - BSA Free Summary

• Description: Novus Biologicals Rabbit ALK-1 Antibody (SR2004) - BSA Free (NBP3-21752) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human ALK-1 (Uniprot #: P37023)
• Specificity: Detects endogenous levels of total ALK-1
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ACVRL1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 56 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ALK-1 Antibody (SR2004) - BSA Free

• activin A receptor type II-like 1
• activin A receptor, type II-like kinase 1
• Activin receptor-like kinase 1
• ACVRL1
• ACVRLK1ORW2
• ALK1
• ALK-1
• ALK1TGF-B superfamily receptor type I
• EC 2.7.11
• HHT
• HHT2EC 2.7.11.30
• serine/threonine-protein kinase receptor R3
• SKR3
• TSR-I

Background

LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK (leukocyte tyrosine kinase) is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK (anaplastic lymphoma kinase) is normally highly expressed, specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACVRL1