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Applications: B/N, Ctrl
LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK (leukocyte tyrosine kinase) is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK (anaplastic lymphoma kinase) is normally highly expressed, specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.
|Product By Gene ID
- EC 2.7.11
- serine/threonine-protein kinase receptor R3
- Activin receptor-like kinase 1
- activin A receptor, type II-like kinase 1
- HHT2EC 22.214.171.124
- ALK1TGF-B superfamily receptor type I
- activin A receptor type II-like 1
Research Areas for ALK-1
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Bioinformatics Tool for ALK-1
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