ALK-1 Products

Description

LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK (leukocyte tyrosine kinase) is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK (anaplastic lymphoma kinase) is normally highly expressed, specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.

Bioinformatics

Entrez	11482 Mouse 25237 Rat 94 Human
Uniprot	AAH42637 Human NM_000020 Human NP_000011 Human NP_000011. Human P37023 Human
Product By Gene ID	94
Alternate Names	activin A receptor type II-like 1 activin A receptor, type II-like kinase 1 Activin receptor-like kinase 1 ACVRLK1ORW2 ALK-1 ALK1TGF-B superfamily receptor type I EC 2.7.11 HHT HHT2EC 2.7.11.30 serine/threonine-protein kinase receptor R3 SKR3 TSR-I

Research Areas for ALK-1

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Protein Kinase