Alas1 Antibody (OTI5D5) [Biotin]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI5D5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Biotin

Alas1 Antibody (OTI5D5) [Biotin] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 57-308 of human ALAS1(NP_000679) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ALAS1
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: >95%

Alternate Names for Alas1 Antibody (OTI5D5) [Biotin]

• 5-aminolevulinic acid synthase 1
• ALAS
• ALAS3
• ALASH
• ALAS-H
• aminolevulinate, delta-, synthase 1
• Delta-ALA synthase 1,5-aminolevulinate synthase, nonspecific, mitochondrial
• Delta-aminolevulinate synthase 1
• EC 2.3.1
• EC 2.3.1.37
• MIG4
• migration-inducing protein 4

Background

Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2 (MIM 301300).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ALAS1