Alas1 Antibody (OTI5D5)

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI5D5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Alas1 Antibody (OTI5D5) Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 57-308 of human ALAS1(NP_000679) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ALAS1
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Western Blot 1:2000

Packaging, Storage & Formulations

• Storage: Store at -20 degrees C. Avoid freeze/thaw cycles.
• Buffer: Lyophilized powder ( 1X PBS, pH 7.3,)
• Preservative: 8% Trehalose
• Purity: >95%
• Reconstitution Instructions: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process.

Alternate Names for Alas1 Antibody (OTI5D5)

• 5-aminolevulinic acid synthase 1
• ALAS
• ALAS3
• ALASH
• ALAS-H
• aminolevulinate, delta-, synthase 1
• Delta-ALA synthase 1,5-aminolevulinate synthase, nonspecific, mitochondrial
• Delta-aminolevulinate synthase 1
• EC 2.3.1
• EC 2.3.1.37
• MIG4
• migration-inducing protein 4

Background

Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2 (MIM 301300).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ALAS1