AKT2 Antibody (302501) [FITC]

• Reactivity: Hu
• Applications: IHC, CyTOF-ready, Flow
• Clone: 302501
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

AKT2 Antibody (302501) [FITC] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Akt2
  Asn2-Glu481
  Accession # P31751
• Specificity: Detects human Akt2. Using direct ELISA, this antibody does not detect recombinant human (rh) Akt1 or rhAkt3.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: AKT2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product FAB23152. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for AKT2 Antibody (302501) [FITC]

• Akt2
• EC 2.7.11
• EC 2.7.11.1
• Murine thymoma viral (v-akt) homolog-2
• PKB beta
• PKBB
• PKBBETA
• PRKBB
• Protein kinase Akt-2
• Protein kinase B beta
• rac protein kinase beta
• RAC-beta serine/threonine-protein kinase
• RAC-beta
• RAC-PK-beta
• v-akt murine thymoma viral oncogene homolog 2

Background

AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AKT2