AKR7A2 Antibody (NBP1-98519)

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Western Blot: AKR7A2 Antibody [NBP1-98519] - Antibody Dilution: 1.0ug/ml Sample Tissue: Human Liver.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

AKR7A2 Antibody Summary

Immunogen
The immunogen for this antibody is AKR7A2 - N-terminal region. Peptide sequence SETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQ.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AKR7A2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for AKR7A2 Antibody

  • AFAR1
  • AFARAFB1-AR1
  • AFB1 aldehyde reductase 1
  • AFB1-AR 1
  • aflatoxin B1 aldehyde reductase member 2
  • aflatoxin beta1 aldehyde reductase
  • AKR7
  • aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
  • Aldoketoreductase 7
  • EC 1.1.1.n11
  • SSA reductase
  • Succinic semialdehyde reductase

Background

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AKR7A2
Uniprot

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