AG-3/AGR3 Antibody (774855) [Alexa Fluor® 594]

• Applications: WB, IHC
• Clone: 774855
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

AG-3/AGR3 Antibody (774855) [Alexa Fluor® 594] Summary

• Immunogen: E. coli-derived recombinant human AG-3
  Ile22-Leu166
  Accession # Q8TD06
• Specificity: Detects human AG-3 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human AG-2 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

AG-3 (Anterior gradient protein 3; also known as AGR3 and BCMP11) is a 17 kDa (predicted) member of the AGR family of proteins. It is expressed by intestinal epithelial and breast cancer cells. AG-3 is presumably secreted and binds to both alpha -dystroglycan and C4.4a/LYPD3. Mature human AG-3 is 145 amino acids (aa) in length (aa 22‑166). Over aa 22-166, human AG-3 shares 92% amino acid sequence identity with mouse AG-3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.