ADAM15 Antibody (MM0078-9H34) - Azide and BSA Free

Western Blot: ADAM15 Antibody (MM0078-9H34) [NBP2-12017] - Lysates of HEK293 cells over human ADAM15.

Product Discontinued

ADAM15 Antibody (MM0078-9H34) - Azide and BSA Free Summary

• Immunogen: Human recombinant ADAM15 (extracellular domain)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADAM15
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:100
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for ADAM15 Antibody (MM0078-9H34) - Azide and BSA Free

• ADAM 15
• ADAM metallopeptidase domain 15
• ADAM15
• disintegrin-like, and cysteine-rich protein 15
• EC 3.4.24
• MDC15
• MDC-15
• Metargidin

Background

ADAM15 is encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADAM15
• Entrez:
  • 8751(Human)
• Uniprot:
  • Q13444()